April 24-26, 1981
- Edwin Moses won his 60th consecutive 400m hurdle final in 48.61
- USC set a World Record in the shuttle hurdles, clocking 55.25
- Suleiman Nyambui of UTEP became not only the first runner to break 29 minutes for 10000m at the Relays, but also the first to break 28 minutes with his time of 27:58.3
- Karin Smith set a Collegate Record in the javelin with a toss of 210-11
- Meg Ritchie set a Collegate Record in the discus with a throw of 221-5, a mark which remains the meet record
- Jane Frederick scored 6166 points in the heptathlon, which would have been a World Record except for a hand timed 800m
- John Muir High School won the HS Division 4X400m relay in 3:13.71, a mark which remains the meet record
